Structure of PDB 7us2 Chain C Binding Site BS03

Receptor Information
>7us2 Chain C (length=347) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEAKYQEKQRKREAEERRRFPLEQRLKEHIIGQESAIATVGAAIRRKENG
WYDEEHPLVFLFLGSSGIGKTELAKQTAKYMHKDAKKGFIRLDMSEFQER
HEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDQVDKAHPDVLTIM
LQLFDEGRLTDGKGKTIDCKDAIFIMTSNVASDEIAQHALQLRQEALEMS
RNRIAETISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQ
LVNKELNFWAKRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVER
RVVNQLAAAYEQDLLPGGCTLRITVEPKLRLEIIDKDSKTRRLDIRA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7us2 Chain C Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7us2 PARL-cleaved Skd3 (human ClpB) E455Q Nucleotide Binding Domain hexamer bound to ATPgammaS, open conformation
Resolution2.76 Å
Binding residue
(original residue number in PDB)		T388 D454
Binding residue
(residue number reindexed from 1)		T71 D137
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.1.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

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Molecular Function
External links
PDB RCSB:7us2, PDBe:7us2, PDBj:7us2
PDBsum7us2
PubMed37163603
UniProtQ9H078|CLPB_HUMAN Mitochondrial disaggregase (Gene Name=CLPB)

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