Structure of PDB 7tay Chain C Binding Site BS03

Receptor Information
>7tay Chain C (length=377) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NIRKSHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLA
MHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGL
YYGSYTFLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSA
IPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHE
TGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGD
PDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILA
LIPLLHTSKQRSMMFRPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQ
LASVLYFLLILVLMPTAGTIENKLLKW
Ligand information
Ligand IDPQU
InChIInChI=1S/C21H17N3O4/c1-21(15-12-13-18(22-14-15)27-17-10-6-3-7-11-17)19(25)24(20(26)28-21)23-16-8-4-2-5-9-16/h2-14,23H,1H3/t21-/m0/s1
InChIKeyQOFLFGUNPBNKDO-NRFANRHFSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01CC1(OC(=O)N(Nc2ccccc2)C1=O)c1cnc(Oc2ccccc2)cc1
OpenEye OEToolkits 2.0.7CC1(C(=O)N(C(=O)O1)Nc2ccccc2)c3ccc(nc3)Oc4ccccc4
CACTVS 3.385C[C]1(OC(=O)N(Nc2ccccc2)C1=O)c3ccc(Oc4ccccc4)nc3
OpenEye OEToolkits 2.0.7C[C@@]1(C(=O)N(C(=O)O1)Nc2ccccc2)c3ccc(nc3)Oc4ccccc4
CACTVS 3.385C[C@]1(OC(=O)N(Nc2ccccc2)C1=O)c3ccc(Oc4ccccc4)nc3
FormulaC21 H17 N3 O4
Name(5S)-3-anilino-5-methyl-5-(6-phenoxypyridin-3-yl)-1,3-oxazolidine-2,4-dione
ChEMBL
DrugBank
ZINC
PDB chain7tay Chain C Residue 1003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7tay Conformation Switch of Rieske ISP subunit is revealed by the Crystal Structure of Bacterial Cytochrome bc1 in Complex with Azoxystrobin
Resolution2.95 Å
Binding residue
(original residue number in PDB)		M124 F128 Y131 G142 V145 I146 P270 E271 Y273 F274
Binding residue
(residue number reindexed from 1)		M122 F126 Y129 G140 V143 I144 P268 E269 Y271 F272
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008121 ubiquinol-cytochrome-c reductase activity
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0048039 ubiquinone binding
Biological Process
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
GO:0022904 respiratory electron transport chain
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0031966 mitochondrial membrane
GO:0045275 respiratory chain complex III

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tay, PDBe:7tay, PDBj:7tay
PDBsum7tay
PubMed
UniProtP00157|CYB_BOVIN Cytochrome b (Gene Name=MT-CYB)

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