Structure of PDB 7c52 Chain C Binding Site BS03

Receptor Information

>7c52 Chain C (length=311) Species: 1050 (Thermochromatium tepidum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

CEGPPPGTEQIGYRGVGMENYYNKRQRALSIQANQPVESLPAADSTGPKA
SEVYQNVQVLKDLSVGEFTRTMVAVTTWVSPKEGCNYCHVPGNWASDDIY
TKVVSRRMFELVRAANSDWKAHVAETGVTCYTCHRGNPVPKYAWVTDPGP
KYPSGLKPTGQNYGSKTVAYASLPFDPLTPFLDQANEIRITGNAALAGSN
PASLKQAEWTFGLMMNISDSLGVGCTFCHNTRAFNDWTQSTPKRTTAWYA
IRHVRDINQNYIWPLNDVLPASRKGPYGDPLRVSCMTCHQAVNKPLYGAQ
MAKDYPGLYKT

Ligand information

Ligand ID

HEM

InChI

InChI=1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+2/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;

InChIKey

KABFMIBPWCXCRK-RGGAHWMASA-L

SMILES

Software	SMILES
OpenEye OEToolkits 1.7.6	Cc1c2n3c(c1CCC(=O)O)C=C4C(=C(C5=[N]4[Fe]36[N]7=C(C=C8N6C(=C5)C(=C8C)C=C)C(=C(C7=C2)C)C=C)C)CCC(=O)O
CACTVS 3.385	CC1=C(CCC(O)=O)C2=Cc3n4[Fe]5\|6\|N2=C1C=c7n5c(=CC8=N\|6C(=Cc4c(C)c3CCC(O)=O)C(=C8C=C)C)c(C)c7C=C
ACDLabs 12.01	C=1c3c(c(c4C=C5C(=C(C=6C=C7C(=C(C8=CC=2C(=C(C=1N=2[Fe](n34)(N5=6)N78)CCC(=O)O)C)\C=C)C)\C=C)C)C)CCC(=O)O

Formula

C34 H32 Fe N4 O4

Name

PROTOPORPHYRIN IX CONTAINING FE;
HEME

PDB chain

7c52 Chain C Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7c52 Crystal structure of a photosynthetic LH1-RC in complex with its electron donor HiPIP.
Resolution	2.89 Å
Binding residue (original residue number in PDB)	R211 I212 T213 F233 M236 S240 C247 C250 H251 F256 N257 R266 A269 W270 R274
Binding residue (residue number reindexed from 1)	R189 I190 T191 F211 M214 S218 C225 C228 H229 F234 N235 R244 A247 W248 R252
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005506	iron ion binding
GO:0009055	electron transfer activity
GO:0020037	heme binding

	Biological Process
GO:0019684	photosynthesis, light reaction

	Cellular Component
GO:0030077	plasma membrane light-harvesting complex

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Molecular Function

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Cellular Component

External links

PDB	RCSB:7c52, PDBe:7c52, PDBj:7c52
PDBsum	7c52
PubMed	33597527
UniProt	D2Z0P5\|CYCR_THETI Photosynthetic reaction center cytochrome c subunit (Gene Name=pufC)

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