Structure of PDB 6yuf Chain C Binding Site BS03

Receptor Information
>6yuf Chain C (length=456) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YITKIVIQGFKSYKDYTVIEPLSPHHNVIVGRNGSGKSNFFAAIRFVLSD
AYTHLSREERQALLHEGPGATVMSAYVEVTFANADNRFPTGKSEVVLRRT
IGLKKDEYSLDKKTVSKTEVINLLESAGFSRSNPYYIVPQGRVTSLTNAK
DSERLELLKEVAGTQIYENRRAESNKIMDETIQKSEKIDELLQYIEERLR
ELEEEKNDLAVYHKKDNERRCLEYAIYSREHDEINSVLDSSNAIVKKLHK
INEALKDYGSVNKKAYEQFNNFTKQRDSLLARREELRRSQESISELTTVL
DQRKDEAIERTFKQVAKSFSEIFVKLVPAGRGELVMNRRSISIRVSFNSK
DDEQLNINQLSGGQKSLCALTLIFAIQRCDPAPFNILDECDANLDAQYRS
AIAAMVKEMSKTSQFICTTFRPEMVKVADNFYGVMFNHKVSTVESISKEE
AMAFVE
Ligand information
Ligand IDBEF
InChIInChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
InChIKeyOGIAHMCCNXDTIE-UHFFFAOYSA-K
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[Be-](F)(F)F
ACDLabs 10.04
CACTVS 3.341		F[Be-](F)F
FormulaBe F3
NameBERYLLIUM TRIFLUORIDE ION
ChEMBL
DrugBank
ZINC
PDB chain6yuf Chain C Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6yuf A Structure-Based Mechanism for DNA Entry into the Cohesin Ring.
Resolution3.94 Å
Binding residue
(original residue number in PDB)		S39 Q141
Binding residue
(residue number reindexed from 1)		S38 Q140
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0061776 topological DNA co-entrapment activity
Biological Process
GO:0007064 mitotic sister chromatid cohesion
GO:0031619 homologous chromosome orientation in meiotic metaphase I
GO:0051276 chromosome organization
GO:0051301 cell division
GO:0140588 chromatin looping
Cellular Component
GO:0000779 condensed chromosome, centromeric region
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005829 cytosol
GO:0008278 cohesin complex
GO:0030892 mitotic cohesin complex
GO:0030893 meiotic cohesin complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6yuf, PDBe:6yuf, PDBj:6yuf
PDBsum6yuf
PubMed32755595
UniProtO42649|SMC3_SCHPO Structural maintenance of chromosomes protein 3 (Gene Name=psm3)

[Back to BioLiP]