Structure of PDB 6rjg Chain C Binding Site BS03

Receptor Information
>6rjg Chain C (length=814) Species: 1268061 (Streptococcus thermophilus DGCC 7710) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DLVLGLDIGIGSVGVGILNKVTGEIIHKNSRIFPAAQAENNLVRRTNRQG
RRLTRRKKHRRVRLNRLFEESGLITDFTKISINLNPYQLRVKGLTDELSN
EELFIALKNMVKHRGISYLGDYAQIVKENSKQLETKTPGQIQLERYQTYG
QLRGDFTVEKDGKKHRLINVFPTSAYRSEALRILQTQQEFNPQITDEFIN
RYLEILTGKRKYYHGPGNEKSRTDYGRYRTSGETLDNIFGILIGKCTFYP
DEFRAAKASYTAQEFNLLNDLNNLLSKEQKNQIINYVKNEKAMGPAKLFK
YIAKLLSCDVADIKGYRIDKSGKAEIHTFEAYRKMKTLETLDIEQMDRET
LDKLAYVLTLNTEREGIQEALEHEFADGSFSQKQVDELVQFRKANSSIFG
KGWHNFSVKLMMELIPELYETSEEQMTILTRLGKQKTTSSSNKTKYIDEK
LLTEEIYNPVVAKSVRQAIKIVNAAIKEYGDFDNIVIEASRVVLNALQEH
FRAHKIDTKVSVVEDSILFSYQVDSKFNRKISDATIYATRQAKVGKDKAD
ETYVLGKIKDIYTQDGYDAFMKIYKKDKSKFLMYRHDPQTFEKVIEPILE
NPFLKYKEEHGYIRKYSKKGNGPEIKSLKYYDSKLGNHIDITPKDSNNKV
VLQSVSPWRADVYFNKTTGKYEILGLKYADLQFEKGTGTYKISQEKYNDI
KKKEGVDSDSEFKFTLYKNDLLLVKDTETKEQQLFRFLSRTMPKQKHYVE
LKPYDKQKFEGGEALIKVLGNVANSGQCKKGLGKSNISIYKVRTDVLGNQ
HIIKNEGDKPKLDF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6rjg Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		S940 K941 G943 N944 V962 S1046 M1049 Q1084
Binding residue
(residue number reindexed from 1)		S633 K634 G636 N637 V655 S739 M742 Q777
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6rjg, PDBe:6rjg, PDBj:6rjg
PDBsum6rjg
PubMed31604602
UniProtQ03LF7|CAS9A_STRTD CRISPR-associated endonuclease Cas9 1 (Gene Name=cas9-1)

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