Structure of PDB 6pht Chain C Binding Site BS03

Receptor Information
>6pht Chain C (length=343) Species: 1658765 (Marinobacter subterrani) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMKTVFSPLHSRRHVKTELDGGLLIEPHEKPSRAETILARVKDQALGEIL
EPEEFGLGPVKRVHTADYVSFLETCWDEWVAAGKRGEAIPTFWVGRGMRA
RLPKDIDGRLGYYSLGADTSISDGTWEAARASANVALTAQKLVAEGERAA
FALCRPPGHHAHADVFGGYCFFNNAAIAAQAFRDQGYGKVAVLDVDFHHG
NGTQAIFYDRSDVLTISLHGDPDLVFPHFLGFEDETGEGDGEAYNLNIVF
PPDTPFSIWSQGLEKACERIRTFAPDALVVALGVDTFEEDPISFFKLTSG
DYLKLGKRLEQLGLPTVFTMEGGYDVDAIGVNAVNVMQGFEGK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6pht Chain C Residue 405 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6pht Structure and Function of the Acetylpolyamine Amidohydrolase from the Deep Earth HalophileMarinobacter subterrani.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D195 H197 D284
Binding residue
(residue number reindexed from 1)		D196 H198 D285
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004407 histone deacetylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006338 chromatin remodeling

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Molecular Function
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Biological Process
External links
PDB RCSB:6pht, PDBe:6pht, PDBj:6pht
PDBsum6pht
PubMed31436969
UniProtA0A0J7JFD7

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