Structure of PDB 6p7e Chain C Binding Site BS03

Receptor Information
>6p7e Chain C (length=672) Species: 10760 (Escherichia phage T7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVSAIAANALLESVTKFHCGVIYDYSTAEYVSYRPSDFGAYLDALEAEV
ARGGLIVFHNGHKYDVPALTKLAKLQLNREFHLPRENCIDTLVLSRLIHS
NLKDTDMGLLRSGKLPGKRFGSHALEAWGYRLGEMKGEYKDDFKRMLEEQ
GEEYVDGMEWWNFNEEMMDYNVQDVVVTKALLEKLLSDKHYFPPEIDFTD
VGYTTFWSESLEAVDIEHRAAWLLAKQERNGFPFDTKAIEELYVELAARR
SELLRKLTETFGSWYQPKGGTEMFCHPRTGKPLPKYPRDTREYVAGAPYT
PVEHVVFNPSSRDHIQKKLQEAGWVPTKYTDKGAPVVDDEVLEGVRVDDP
EKQAAIDLIKEYLMIQKRIGQSAEGDKAWLRYVAEDGKIHGSVNPNGAVT
GRATHAFPNLAQIPGVRSPYGEQCRAAFGAEHHLDGITGKPWVQAGIDAS
GLELRCLAHFMARFDNGEYAHEILNGDIHTKNQIAAELPTRDNAKTFIYG
FLYGAGDEKIGQIVGAGKERGKELKKKFLENTPAIAALRESIQQTLVESS
QWQVKWKRRWIKGLDGRKVHVRSPHAALNTLLQSAGALICKLWIIKTEEM
LVEKGLKHGWDGDFAYMAWVHDEIQVGCRTEEIAQVVIETAQEAMRWVGD
HWNFRCLLDTEGKMGPNWAICH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6p7e Combined Solution and Crystal Methods Reveal the Electrostatic Tethers That Provide a Flexible Platform for Replication Activities in the Bacteriophage T7 Replisome.
Resolution3.001 Å
Binding residue
(original residue number in PDB)		R490 I569 I593 R687
Binding residue
(residue number reindexed from 1)		R463 I542 I561 R655
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006302 double-strand break repair
GO:0039693 viral DNA genome replication
GO:0090592 DNA synthesis involved in DNA replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6p7e, PDBe:6p7e, PDBj:6p7e
PDBsum6p7e
PubMed31659895
UniProtP00581|DPOL_BPT7 DNA-directed DNA polymerase (Gene Name=5)

[Back to BioLiP]