Structure of PDB 6p71 Chain C Binding Site BS03

Receptor Information
>6p71 Chain C (length=1111) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRE
TFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGL
IKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGR
YIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETL
ARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYV
YGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTL
RYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRE
RMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHK
RRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAA
YARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNR
IAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANR
ALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVD
GNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLAD
GPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIER
YEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVG
RTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLR
RGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVED
MPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFD
GAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGK
TPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHA
RSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKS
DDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDN
PVDIFEGLASK
Ligand information
Receptor-Ligand Complex Structure
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PDB6p71 Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Resolution2.92 Å
Binding residue
(original residue number in PDB)		R420 K838 K846 H999
Binding residue
(residue number reindexed from 1)		R413 K831 K839 H992
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6p71, PDBe:6p71, PDBj:6p71
PDBsum6p71
PubMed31965171
UniProtQ8RQE9|RPOB_THET8 DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

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