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Receptor Information

>6cim Chain C (length=602) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEH
RQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQ
IFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSV
DEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVV
KESCDGMGDVSEKVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELC
CKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFI
FRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHA
ENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNA
AEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNG
NFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKE
CPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDG
SIGAWNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNA
HN

>6cim Chain G (length=52) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ggtttttgtctggcttcacacttgatttgcatcactgtgtaagacaggcc
ag

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6cim Cracking the DNA Code for V(D)J Recombination.
Resolution	3.6 Å
Binding residue (original residue number in PDB)	N443 R848 M849 N965 R969
Binding residue (residue number reindexed from 1)	N48 R447 M448 N560 R564

Enzyme Commision number

2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-

	Molecular Function
GO:0004519	endonuclease activity
GO:0043565	sequence-specific DNA binding
GO:0061630	ubiquitin protein ligase activity

	Biological Process
GO:0033151	V(D)J recombination

PDB	RCSB:6cim, PDBe:6cim, PDBj:6cim
PDBsum	6cim
PubMed	29628308
UniProt	P15919\|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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Structure of PDB 6cim Chain C Binding Site BS03