Structure of PDB 6cil Chain C Binding Site BS03

Receptor Information
>6cil Chain C (length=589) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARRQAD
ELEAIGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHAL
RNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTI
AKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMG
DVSEKEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLAD
ESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKL
VREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWR
SNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLE
IGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQE
TVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSF
NSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGQSGNKLF
RRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN
Ligand information
>6cil Chain G (length=53) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggtttttgtctggcttcacacttgatttgcatcactgtgtaagacaggcc
aga
Receptor-Ligand Complex Structure
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PDB6cil Cracking the DNA Code for V(D)J Recombination.
Resolution4.15 Å
Binding residue
(original residue number in PDB)		M602 M849 N965 R969
Binding residue
(residue number reindexed from 1)		M199 M438 N547 R551
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cil, PDBe:6cil, PDBj:6cil
PDBsum6cil
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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