Structure of PDB 6cik Chain C Binding Site BS03

Receptor Information
>6cik Chain C (length=602) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEH
RQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQ
IFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSV
DEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVV
KESCDGMGDVSEKVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELC
CKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFI
FRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHA
ENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNA
AEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNG
NFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKE
CPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDG
SIGAWNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNA
HN
Ligand information
>6cik Chain G (length=51) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggtttttgtctggcttcacacttgatttgcatcactgtgtaagacaggcc
a
Receptor-Ligand Complex Structure
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PDB6cik Cracking the DNA Code for V(D)J Recombination.
Resolution3.15 Å
Binding residue
(original residue number in PDB)		N443 R446 R848 M849 R969
Binding residue
(residue number reindexed from 1)		N48 R51 R447 M448 R564
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cik, PDBe:6cik, PDBj:6cik
PDBsum6cik
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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