Structure of PDB 6cij Chain C Binding Site BS03

Receptor Information
>6cij Chain C (length=616) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRA
RNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAI
TGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGL
ASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPF
TVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVF
EEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEM
GGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNL
VFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSI
DALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRM
NLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKP
VWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLA
HVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHH
WLYTSKYLQKFMNAHN
Ligand information
>6cij Chain G (length=60) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgggtttttgtctggcttcacacttgatttgcatcactgtgtaagacagg
ccagatccag
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6cij Cracking the DNA Code for V(D)J Recombination.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		N443 G722 L794 I798 G851 N852 E959 Q962 K966 R969
Binding residue
(residue number reindexed from 1)		N52 G331 L403 I407 G460 N461 E568 Q571 K575 R578
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6cij, PDBe:6cij, PDBj:6cij
PDBsum6cij
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

[Back to BioLiP]