Structure of PDB 6cg0 Chain C Binding Site BS03

Receptor Information
>6cg0 Chain C (length=616) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRA
RNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAI
TGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGL
ASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPF
TVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVF
EEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEM
GGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNL
VFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSI
DALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRM
NLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKP
VWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLA
HVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHH
WLYTSKYLQKFMNAHN
Ligand information
>6cg0 Chain G (length=60) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgggtttttgtctggcttcacacttgatttgcatcactgtgtaagacagg
ccagatccag
Receptor-Ligand Complex Structure
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PDB6cg0 Cracking the DNA Code for V(D)J Recombination.
Resolution3.17 Å
Binding residue
(original residue number in PDB)		N443 A720 G722 S723 R773 H795 R848 N850 G851 N852 Q962 K966 R969
Binding residue
(residue number reindexed from 1)		N52 A329 G331 S332 R382 H404 R457 N459 G460 N461 Q571 K575 R578
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cg0, PDBe:6cg0, PDBj:6cg0
PDBsum6cg0
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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