Structure of PDB 5zrd Chain C Binding Site BS03

Receptor Information
>5zrd Chain C (length=529) Species: 271848 (Burkholderia thailandensis E264) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APRVRRSVRDLQKRYDNGEKKPLEDLVRAWVGIQALPPSDPKSFFALGGY
HGEPFQYRKPVDALPQDDIYPYWGGYCNHGNVLFPTWHRMYVYKLEEALQ
SIVPGVSMPFWDETDEYTLKHGIPSILTQEKFELDGKQIDNPLRSFVLPV
ALSDRLPGDGNIYEKPKGYVTVRYPLSGLVGTPEALEQTKIHNAKFPLPE
KNTELLNSNVRAWLKGDSPTPGDPDPTRNGVYAKYVRCLSAPNYTVFSNT
TSASVWNSSNPGLVTPVESPHNDIHLAVGGFDYGGDEIGQIAGANGDMGE
NNTAGMDPIFFFHHCNVDRMFWVWQKQTGHTDRLDIIRNYPGTNASDSQG
PTPGFAPGESLNLTTPLNPFKKASGEAYTSEDCINIERQLGFTYGPGSLD
DATPELKSLLAVPSGNSTKKLTVTGIDRAQIQGSFIMKAYASVTDANGKT
REYYLGHKSILSRWNVVQCANCLTHLDIVAHFPLSAMPADDVPKAKFRVE
FIHRGGGVPSAAKAAIDKVSALQPKFEVS
Ligand information
Ligand IDO
InChIInChI=1S/H2O/h1H2
InChIKeyXLYOFNOQVPJJNP-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		O
CACTVS 3.341[O]
FormulaO
NameOXYGEN ATOM
ChEMBLCHEMBL1098659
DrugBankDB09145
ZINC
PDB chain5zrd Chain C Residue 606 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zrd Structural Basis for Highly Efficient Production of Catechol Derivatives at Acidic pH by Tyrosinase from Burkholderia thailandensis
Resolution2.3 Å
Binding residue
(original residue number in PDB)		H276 H280
Binding residue
(residue number reindexed from 1)		H271 H275
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.18.1: tyrosinase.
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0004503 tyrosinase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5zrd, PDBe:5zrd, PDBj:5zrd
PDBsum5zrd
PubMed
UniProtQ2T7K1

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