Structure of PDB 5w75 Chain C Binding Site BS03

Receptor Information
>5w75 Chain C (length=387) Species: 309803 (Thermotoga neapolitana DSM 4359) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKPHVNVGTIGHVDHGKSTLTAAITKYLSLKGLAQYVPYDQIDKAPEEKA
RGITINITHVEYETEKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAA
TDGPMPQTREHVLLARQVGVPYMIVFINKTDMVDDPELIELVEMEVRDLL
SQYEYPGDEVPVIKGSALKALEANHEAYKPIQELLDAMDNYIPDPQRDVD
KPFLMPIEDVFSITGRGTVVTGRIERGRIRPGDEVEIIGLSEIRKTVVTS
VEMFRKELDEGIAGDNVGCLLRGIDKDEVERGQVLAAPGSIKPHKRFKAE
VYVLKKEEGGRHTPFFKGYKPQFYIRTTDVTGEIVLPEGVEMVMPGDHVE
MEIELIYPVAIEKGQRFAIREGGRTVGAGVVTEVIEL
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain5w75 Chain G Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5w75 Structural and Dynamics Comparison of Thermostability in Ancient, Modern, and Consensus Elongation Factor Tus.
Resolution2.298 Å
Binding residue
(original residue number in PDB)		T222 G223
Binding residue
(residue number reindexed from 1)		T214 G215
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5w75, PDBe:5w75, PDBj:5w75
PDBsum5w75
PubMed29276038
UniProtB9K884|EFTU_THENN Elongation factor Tu (Gene Name=tuf)

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