Structure of PDB 5eg6 Chain C Binding Site BS03

Receptor Information
>5eg6 Chain C (length=413) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLM
GSGWKKKKEQMERDGCSEQESQPCAFIGIGNSEMQQLNLEGKNYCTAKTL
YISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKQSLKNADLC
IASGTKVALFNRLTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGE
EFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQL
HKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIIST
DKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGDVAMLELTGQNFTPNLRV
WFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGV
IYSTSLTFTYTPE
Ligand information
Receptor-Ligand Complex Structure
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PDB5eg6 CSL-RITA complex bound to DNA
Resolution2.094 Å
Binding residue
(original residue number in PDB)
K90 R91 F92 K192 R218 T223
Binding residue
(residue number reindexed from 1)
K38 R39 F40 K138 R162 T164
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5eg6, PDBe:5eg6, PDBj:5eg6
PDBsum5eg6
PubMed
UniProtP31266|SUH_MOUSE Recombining binding protein suppressor of hairless (Gene Name=Rbpj)

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