Structure of PDB 4z3c Chain C Binding Site BS03

Receptor Information
>4z3c Chain C (length=44) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRKRCGTCEPCRRLENCGACTSCTNRRTHQICKLRKCEVLKKKV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4z3c Chain C Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4z3c DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Resolution1.57 Å
Binding residue
(original residue number in PDB)		C57 C60 C63 C89
Binding residue
(residue number reindexed from 1)		C5 C8 C11 C37
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.80: methylcytosine dioxygenase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:4z3c, PDBe:4z3c, PDBj:4z3c
PDBsum4z3c
PubMed29276034
UniProtO43151|TET3_HUMAN Methylcytosine dioxygenase TET3 (Gene Name=TET3)

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