Structure of PDB 4eoy Chain C Binding Site BS03

Receptor Information
>4eoy Chain C (length=123) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPSLKDEVSFENRVAETHKIRSKYPNRIPVVIERANRSNLPIIEKKKFLV
PMNMLVGEFKFILHQHINQSAYGSNMKLFRERTIYLFVNNIVPKTGLLMQ
DLYEMYKDEDGYLYMEYSSESSL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4eoy Chain C Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4eoy Structural characterization and inhibition of the Plasmodium Atg8-Atg3 interaction.
Resolution2.22 Å
Binding residue
(original residue number in PDB)		R35 N37 S39 L41
Binding residue
(residue number reindexed from 1)		R34 N36 S38 L40
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008429 phosphatidylethanolamine binding
GO:0046872 metal ion binding
Biological Process
GO:0000045 autophagosome assembly
GO:0000422 autophagy of mitochondrion
GO:0006914 autophagy
GO:0006995 cellular response to nitrogen starvation
GO:0097352 autophagosome maturation
Cellular Component
GO:0000421 autophagosome membrane
GO:0005829 cytosol
GO:0016020 membrane
GO:0020011 apicoplast
GO:0031410 cytoplasmic vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4eoy, PDBe:4eoy, PDBj:4eoy
PDBsum4eoy
PubMed22982544
UniProtQ8IJK2

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