Structure of PDB 3ugx Chain C Binding Site BS03

Receptor Information
>3ugx Chain C (length=358) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NHVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVY
VSLTCAFRYGQLSFRRDLYFSQVQVFPPVGASGATTRLQESLIKKLGANT
YPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEIKAFATHSTDVEEDKIP
KKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVSLSKEIYY
HGEPIPVTVAVTNSTEKTVKKIKVLVEQVTNVVLYSSDYYIKTVAAEEAQ
EKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEG
IDKTVMGILVSYQIKVKLTVSGLLSSEVATEVPFRLMHPQPEDDENFVFE
EFARQNLK
Ligand information
Ligand IDPTD
InChIInChI=1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
InChIKeySXRSQZLOMIGNAQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CC=O)CC=O
ACDLabs 10.04
CACTVS 3.341		O=CCCCC=O
FormulaC5 H8 O2
NamePENTANEDIAL
ChEMBLCHEMBL1235482
DrugBankDB03266
ZINCZINC000001729593
PDB chain3ugx Chain C Residue 407 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ugx Crystal Structure of p44, a Constitutively Active Splice Variant of Visual Arrestin.
Resolution2.649 Å
Binding residue
(original residue number in PDB)		E212 T310 P352 F353 R354
Binding residue
(residue number reindexed from 1)		E197 T295 P333 F334 R335
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001664 G protein-coupled receptor binding
Biological Process
GO:0002031 G protein-coupled receptor internalization
GO:0007165 signal transduction
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0005829 cytosol
GO:0016020 membrane
GO:0042995 cell projection

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ugx, PDBe:3ugx, PDBj:3ugx
PDBsum3ugx
PubMed22306737
UniProtP08168|ARRS_BOVIN S-arrestin (Gene Name=SAG)

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