Structure of PDB 3s28 Chain C Binding Site BS03

Receptor Information
>3s28 Chain C (length=781) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NEVLALLSRVEAKGKGILQQNQIIAEFEALPEQTRKKLEGGPFFDLLKST
QEAIVLPPWVALAVRPRPGVWEYLRVNLHALVVEELQPAEFLHFKEELVD
GVKNGNFTLELDFEPFNASIPRPTLHKYIGNGVDFLNRHLSAKLFHDKES
LLPLLKFLRLHSHQGKNLMLSEKIQNLNTLQHTLRKAEEYLAELKSETLY
EEFEAKFEEIGLERGWGDNAERVLDMIRLLLDLLEAPDPCTLETFLGRVP
MVFNVVILSPHGYFAQDNVLGYPDTGGQVVYILDQVRALEIEMLQRIKQQ
GLNIKPRILILTRLLPDAVGTTCGERLERVYDSEYCDILRVPFRTEKGIV
RKWISRFEVWPYLETYTEDAAVELSKELNGKPDLIIGNYSDGNLVASLLA
HKLGVTQCTIAHALEKTKYPDSDIYWKKLDDKYHFSCQFTADIFAMNHTD
FIITSTFQEIAGSKETVGQYESHTAFTLPGLYRVVHGIDVFDPKFNIVSP
GADMSIYFPYTEEKRRLTKFHSEIEELLYSDVENKEHLCVLKDKKKPILF
TMARLDRVKNLSGLVEWYGKNTRLRELANLVVVGGDRRKESKDNEEKAEM
KKMYDLIEEYKLNGQFRWISSQMDRVRNGELYRYICDTKGAFVQPALYEA
FGLTVVEAMTCGLPTFATCKGGPAEIIVHGKSGFHIDPYHGDQAADTLAD
FFTKCKEDPSHWDEISKGGLQRIEEKYTWQIYSQRLLTLTGVYGFWKHVS
NLDRLEARRYLEMFYALKYRPLAQAVPLAQD
Ligand information
Ligand IDNHF
InChIInChI=1S/C6H10O5/c7-1-4-6(10)5(9)3(8)2-11-4/h4-7,9-10H,1-2H2/t4-,5-,6-/m1/s1
InChIKeyOCLOLUFOLJIQDC-HSUXUTPPSA-N
SMILES
SoftwareSMILES
CACTVS 3.341OC[C@H]1OCC(=O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C1C(=O)C(C(C(O1)CO)O)O
CACTVS 3.341OC[CH]1OCC(=O)[CH](O)[CH]1O
OpenEye OEToolkits 1.5.0C1C(=O)[C@H]([C@@H]([C@H](O1)CO)O)O
ACDLabs 10.04O=C1COC(CO)C(O)C1O
FormulaC6 H10 O5
Name1,5-anhydro-D-fructose
ChEMBLCHEMBL1234723
DrugBank
ZINC
PDB chain3s28 Chain C Residue 904 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3s28 The Structure of Sucrose Synthase-1 from Arabidopsis thaliana and Its Functional Implications.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		H438 E675 A676 F677
Binding residue
(residue number reindexed from 1)		H412 E649 A650 F651
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.13: sucrose synthase.
Gene Ontology
Molecular Function
GO:0016157 sucrose synthase activity
GO:0016757 glycosyltransferase activity
Biological Process
GO:0001666 response to hypoxia
GO:0005985 sucrose metabolic process
GO:0006970 response to osmotic stress
GO:0009409 response to cold
GO:0009413 response to flooding
GO:0009414 response to water deprivation
GO:0009744 response to sucrose
GO:0009749 response to glucose
GO:0010555 response to mannitol
GO:0071456 cellular response to hypoxia
GO:0072708 response to sorbitol
Cellular Component
GO:0005829 cytosol
GO:0009506 plasmodesma

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3s28, PDBe:3s28, PDBj:3s28
PDBsum3s28
PubMed21865170
UniProtP49040|SUS1_ARATH Sucrose synthase 1 (Gene Name=SUS1)

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