Structure of PDB 2woj Chain C Binding Site BS03

Receptor Information
>2woj Chain C (length=284) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VEPNLHSLITSTTHKWIFVGGKGGVGKTTSSCSIAIQMALSQPNKQFLLI
STDPAHNLSDAFGEKFGKDARKVTGMNNLSCMEIDPSAALKDMNDLADLT
GSIPGIDEALSFMEVMKHIKRQTFDTVIFDTAPTGHTLRFLQLPNTLSKL
LESGKLNELKANVETIRQQFTDPDLTTFVCVCISEFLSLYETERLIQELI
SYDMDVNSIIVNQLLFACKRCQARWKMQKKYLDQIDELYEDFHVVKMPLC
AGEIRGLNNLTKFSQFLNKEYNPITDGKVIYELE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2woj Chain C Residue 1352 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2woj The Structural Basis of Tail-Anchored Membrane Protein Recognition by Get3.
Resolution1.994 Å
Binding residue
(original residue number in PDB)		C285 C288
Binding residue
(residue number reindexed from 1)		C218 C221
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G28 G30 K31 T32 T33 D57
Catalytic site (residue number reindexed from 1) G24 G26 K27 T28 T29 D53
Enzyme Commision number 3.6.-.-
Gene Ontology
Molecular Function
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0044183 protein folding chaperone
GO:0046872 metal ion binding
GO:0051082 unfolded protein binding
Biological Process
GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0006457 protein folding
GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0009408 response to heat
GO:0010038 response to metal ion
GO:0016192 vesicle-mediated transport
GO:0034599 cellular response to oxidative stress
GO:0045048 protein insertion into ER membrane
GO:0046685 response to arsenic-containing substance
GO:0071816 tail-anchored membrane protein insertion into ER membrane
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0043529 GET complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2woj, PDBe:2woj, PDBj:2woj
PDBsum2woj
PubMed19675567
UniProtQ12154|GET3_YEAST ATPase GET3 (Gene Name=GET3)

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