Structure of PDB 2bs4 Chain C Binding Site BS03

Receptor Information
>2bs4 Chain C (length=254) Species: 844 (Wolinella succinogenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTNESILESYSGVTPERKKSRMPAKLDWWQSATGLFLGLFMIGHMFFVST
ILLGDNVMLWVTKKFELDFIFEGGKPIVVSFLAAFVFAVFIAHAFLAMRK
FPINYRQYLTFKTHKDLMRHGDTTLWWIQAMTGFAMFFLGSVHLYIMMTQ
PQTIGPVSSSFRMVSEWMWPLYLVLLFAVILHGSVGLYRLAVKWGWFDGE
TPDKTRANLKKLKTLMSAFLIVLGLLTFGAYVKKGLEQTDPNIDYKYFDY
KRTH
Ligand information
Ligand IDDMW
InChIInChI=1S/C12H10O2/c1-7-8(2)12(14)10-6-4-3-5-9(10)11(7)13/h3-6H,1-2H3
InChIKeyLGFDNUSAWCHVJN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341CC1=C(C)C(=O)c2ccccc2C1=O
ACDLabs 10.04O=C2c1c(cccc1)C(=O)C(=C2C)C
OpenEye OEToolkits 1.5.0CC1=C(C(=O)c2ccccc2C1=O)C
FormulaC12 H10 O2
Name2,3-DIMETHYL-1,4-NAPHTHOQUINONE
ChEMBLCHEMBL354201
DrugBankDB07669
ZINCZINC000003063275
PDB chain2bs4 Chain E Residue 1244 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2bs4 Experimental Support for the E-Pathway Hypothesis of Coupled Transmembrane Electron and Proton Transfer in Dihemic Quinol:Fumarate Reductase
Resolution2.76 Å
Binding residue
(original residue number in PDB)		F47 V48 T62 F65 L82 I154
Binding residue
(residue number reindexed from 1)		F47 V48 T62 F65 L82 I154
Annotation score1
Enzymatic activity
Enzyme Commision number 1.3.99.1: Deleted entry.
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0006099 tricarboxylic acid cycle
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2bs4, PDBe:2bs4, PDBj:2bs4
PDBsum2bs4
PubMed16380425
UniProtP17413|FRDC_WOLSU Fumarate reductase cytochrome b subunit (Gene Name=frdC)

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