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Receptor Information

>1nen Chain C (length=129) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MIRNVKKQRPVNLDLQTIRFPITAIASILHRVSGVITFVAVGILLWLLGT
SLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFGYLE
ETFEAGKRSAKISFVITVVLSLLAGVLVW

Ligand ID

CDN

InChI

InChI=1S/C58H120O17P2/c1-5-9-13-16-19-22-25-27-30-33-36-40-44-57(62)74-53(48-68-55(60)42-38-12-8-4)50-72-76(64,65)70-46-52(59)47-71-77(66,67)73-51-54(49-69-56(61)43-39-35-32-29-24-21-18-15-11-7-3)75-58(63)45-41-37-34-31-28-26-23-20-17-14-10-6-2/h52-63H,5-51H2,1-4H3,(H,64,65)(H,66,67)/t52-,53+,54+,55?,56?,57?,58-/m0/s1

InChIKey

GKRASOJOCMJQMF-DUXRJKJQSA-N

SMILES

Software	SMILES
CACTVS 3.341	CCCCCCCCCCCCCC[C@H](O)O[C@H](CO[C@H](O)CCCCC)CO[P@](O)(=O)OC[C@H](O)CO[P@](O)(=O)OC[C@@H](CO[C@H](O)CCCCCCCCCCCC)O[C@H](O)CCCCCCCCCCCCCC
ACDLabs 10.04	O=P(O)(OCC(OC(O)CCCCCCCCCCCCCC)COC(O)CCCCC)OCC(O)COP(=O)(OCC(OC(O)CCCCCCCCCCCCCC)COC(O)CCCCCCCCCCCC)O
OpenEye OEToolkits 1.5.0	CCCCCCCCCCCCCCC(O)OC(COC(CCCCC)O)COP(=O)(O)OCC(COP(=O)(O)OCC(COC(CCCCCCCCCCCC)O)OC(CCCCCCCCCCCCCC)O)O
OpenEye OEToolkits 1.5.0	CCCCCCCCCCCCCCC(O)O[C@H](COC(CCCCC)O)CO[P@@](=O)(O)OC[C@@H](CO[P@@](=O)(O)OC[C@@H](COC(CCCCCCCCCCCC)O)O[C@@H](CCCCCCCCCCCCCC)O)O
CACTVS 3.341	CCCCCCCCCCCCCC[CH](O)O[CH](CO[CH](O)CCCCC)CO[P](O)(=O)OC[CH](O)CO[P](O)(=O)OC[CH](CO[CH](O)CCCCCCCCCCCC)O[CH](O)CCCCCCCCCCCCCC

Formula

C58 H120 O17 P2

Name

CARDIOLIPIN

ChEMBL

DrugBank

ZINC

PDB chain

1nen Chain C Residue 308 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1nen Architecture of succinate dehydrogenase and reactive oxygen species generation
Resolution	2.9 Å
Binding residue (original residue number in PDB)	V41 S51 A61 S62 M65 L78 A82 L123 V126 L127 W129
Binding residue (residue number reindexed from 1)	V41 S51 A61 S62 M65 L78 A82 L123 V126 L127 W129
Annotation score	1

Enzyme Commision number

	Molecular Function
GO:0008177	succinate dehydrogenase (quinone) activity
GO:0009055	electron transfer activity
GO:0020037	heme binding
GO:0046872	metal ion binding
GO:0048039	ubiquinone binding

	Biological Process
GO:0006099	tricarboxylic acid cycle
GO:0009060	aerobic respiration
GO:0017004	cytochrome complex assembly
GO:0019646	aerobic electron transport chain

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

PDB	RCSB:1nen, PDBe:1nen, PDBj:1nen
PDBsum	1nen
PubMed	12560550
UniProt	P69054\|DHSC_ECOLI Succinate dehydrogenase cytochrome b556 subunit (Gene Name=sdhC)

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Structure of PDB 1nen Chain C Binding Site BS03