Structure of PDB 1egw Chain C Binding Site BS03

Receptor Information
>1egw Chain C (length=72) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSS
NKLFQYASTDMDKVLLKYTEYN
Ligand information
Receptor-Ligand Complex Structure
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PDB1egw Crystal structure of MEF2A core bound to DNA at 1.5 A resolution.
Resolution1.5 Å
Binding residue
(original residue number in PDB)		G2 R3 I6 K23 R24 K30
Binding residue
(residue number reindexed from 1)		G1 R2 I5 K22 R23 K29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:1egw, PDBe:1egw, PDBj:1egw
PDBsum1egw
PubMed10715212
UniProtQ02078|MEF2A_HUMAN Myocyte-specific enhancer factor 2A (Gene Name=MEF2A)

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