Structure of PDB 4v8q Chain BZ Binding Site BS03

Receptor Information
>4v8q Chain BZ (length=377) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GEFVRTKPHVNVGTIGHVDHGKTTLTAALTYVAAAENPHVEYETAKRHYS
HVDCPGHADYIKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGV
PYIVVFMNKVDMVDDPELLDLVEMEVRDLLNQYEFPGDEVPVIRGSALLA
LEEMHKNPKTKRGENEWVDKIWELLDAIDEYIPTPVRDVDKPFLMPVEDV
FTITGRGTVATGRIERGKVKVGDEVEIVGLAPETRKTVVTGVEMHRKTLQ
EGIAGDNVGLLLRGVSREEVERGQVLAKPGSITPHTKFEASVYILKKEEG
GRHTGFFTGYRPQFYFRTTDVTGVVRLPQGVEMVMPGDNVTFTVELIKPV
ALEEGLRFAIREGGRTVGAGVVTKILE
Ligand information
>4v8q Chain BY (length=62) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggggugaaacggucucgacagggccuuuggacguggguucgacucccac
caccuccaccaA
<<<<<<<............<<<<...>>>>...<<<<<.......>>>>>
>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB4v8q Decoding in the absence of a codon by tmRNA and SmpB in the ribosome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
D87 Y88 K90 N91 F229 T232 R234 E271 M272 H273 R274 V286 G287 L289 R295 R300 R330 H331 T332 Y338 R339 T350 E390 G391
Binding residue
(residue number reindexed from 1)
D59 Y60 K62 N63 F201 T204 R206 E243 M244 H245 R246 V258 G259 L261 R267 R272 R302 H303 T304 Y310 R311 T322 E362 G363
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4v8q, PDBe:4v8q, PDBj:4v8q
PDBsum4v8q
PubMed22422985
UniProtQ5SHN6|EFTU1_THET8 Elongation factor Tu-A (Gene Name=tufA)

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