Structure of PDB 4v9o Chain BV Binding Site BS03

Receptor Information
>4v9o Chain BV (length=690) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNAATMDWMEQEQERG
ITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAV
MVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKT
RLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPAD
MVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNE
IILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERH
ASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERF
GRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILERME
FPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAG
MGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQSG
GRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQ
LKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKP
VLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPL
SEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4v9o Chain BV Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4v9o Control of ribosomal subunit rotation by elongation factor G.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		T24 T62
Binding residue
(residue number reindexed from 1)		T23 T52
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.-
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0097216 guanosine tetraphosphate binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
GO:0032790 ribosome disassembly
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4v9o, PDBe:4v9o, PDBj:4v9o
PDBsum4v9o
PubMed23812721
UniProtP0A6M8|EFG_ECOLI Elongation factor G (Gene Name=fusA)

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