Structure of PDB 8btk Chain BQ Binding Site BS03

Receptor Information

>8btk Chain BQ (length=187) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GVDIRHNKDRKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRL
FMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTVTDDVRVQEVPKLKVC
ALRVTSRARSRILKAGGKILTFDQLALDSPKGRGTVLLSGPRKGREVYRH
FGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8btk Chain BQ Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8btk Molecular basis of the TRAP complex function in ER protein biogenesis.
Resolution	3.5 Å
Binding residue (original residue number in PDB)	A36 R37
Binding residue (residue number reindexed from 1)	A35 R36
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005791	rough endoplasmic reticulum
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0043232	intracellular non-membrane-bounded organelle
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:8btk, PDBe:8btk, PDBj:8btk
PDBsum	8btk
PubMed	37170030
UniProt	F6QKI9

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