Structure of PDB 8ove Chain BN Binding Site BS03

Receptor Information

>8ove Chain BN (length=210) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PKGNNAIPHVHQRKHWNPCSSQKGNVKVFFNQPAQKQRRRRLRLLKAKKI
FPRPLKALRPQVNCPTVRYNMKRRLGRGFSLEELKAAGVKPRYARTIGIR
VDRRRKNKSEEGMNINVQRLKTYMSKLVLFPLNRKKPQKGDATEEEVKAA
TQDRSRYGTAAVGGLVTPAREAPRKVTEEESTKKMYKFLKKNHSAVRFFR
ARNRRAARKE

Ligand information

>8ove Chain BC (length=160) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aacgugucgcgauggaugacuuggcuuccuauuucguugaagaacgcagc
aaagugcgauaagugguaucaauugcagaaucauugcccaaucuuugaac
gcaaacggcgcaugggagaagcucgagccauccccgugcaugccacauuu
cucagugucg

.........................................<<<<<<<<<
....>>>>.....(<<<<......>>........>>>>.)...>>>....
<<.....>><<<<<<<....<<<..>>>....>>>>>>>...........
..........

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8ove A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.
Resolution	2.6 Å
Binding residue (original residue number in PDB)	A35 R39
Binding residue (residue number reindexed from 1)	A34 R38

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:8ove, PDBe:8ove, PDBj:8ove
PDBsum	8ove
PubMed	37985661
UniProt	Q57V55

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