Structure of PDB 7nql Chain BL Binding Site BS03

Receptor Information
>7nql Chain BL (length=137) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDIPLDRLTISYCRSSGPGGQNVNKVNSKAEVRFHLATAEWIAEPVRQKI
AITHKNKINRLGELILTSESSRYQFRNLADCLQKIRDMITEASQTPKEPT
KEDVKLHRIRIENMNRERLRQKRIHSAVKTSRRVDMD
Ligand information
>7nql Chain AV (length=71) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aguaaggucagcuaaauaagcuaucgggcccauaccccgaaaauguuggu
uauacccuucccguacuacca
<<<<.<<..<<<<.....>>>>.<<<<<.......>>>>>....<..<<.
.....>>..>>>.>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7nql Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		G88 N91 R141 R145
Binding residue
(residue number reindexed from 1)		G19 N22 R72 R76
Enzymatic activity
Enzyme Commision number 3.1.1.29: peptidyl-tRNA hydrolase.
Gene Ontology
Molecular Function
GO:0003747 translation release factor activity
Biological Process
GO:0006415 translational termination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7nql, PDBe:7nql, PDBj:7nql
PDBsum7nql
PubMed33878294
UniProtQ14197|ICT1_HUMAN Large ribosomal subunit protein mL62 (Gene Name=MRPL58)

[Back to BioLiP]