Structure of PDB 7o19 Chain BF Binding Site BS03

Receptor Information

>7o19 Chain BF (length=177) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLD
NAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFE
RLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRG
LDITITTTAKSDEEGRALLAAFDFPFR

Ligand information

>7o19 Chain B8 (length=77) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cggugauuggcgcagccugguagcgcacuucguucgggacgaaggggucg
gagguucgaauccucuaucaccgacca

<<<<<<<..<<<<.........>>>>.<<<<<<.....>>>>>>.....<
<<<<.......>>>>>>>>>>>>....

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7o19 Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling.
Resolution	2.9 Å
Binding residue (original residue number in PDB)	S73 V74 A75 R80
Binding residue (residue number reindexed from 1)	S72 V73 A74 R79

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:7o19, PDBe:7o19, PDBj:7o19
PDBsum	7o19
PubMed	34504068
UniProt	P62399\|RL5_ECOLI Large ribosomal subunit protein uL5 (Gene Name=rplE)

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