Structure of PDB 4w2f Chain B0 Binding Site BS03
Receptor Information
>4w2f Chain B0 (length=83) Species:
300852
(Thermus thermophilus HB8) [
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AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNV
GMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPL
Ligand information
>4w2f Chain BB (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
<<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>..
.....>>>.>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
4w2f
Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
R72 R74
Binding residue
(residue number reindexed from 1)
R71 R73
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003735
structural constituent of ribosome
Biological Process
GO:0006412
translation
Cellular Component
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Cellular Component
External links
PDB
RCSB:4w2f
,
PDBe:4w2f
,
PDBj:4w2f
PDBsum
4w2f
PubMed
25306919
UniProt
P60493
|RL27_THET8 Large ribosomal subunit protein bL27 (Gene Name=rpmA)
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