Structure of PDB 8zsz Chain B Binding Site BS03

Receptor Information
>8zsz Chain B (length=315) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRNRGRLLCMLALTFMFMVLEVVVSRVTSSLAMLSDSFHMLSDVLALVVA
LVAERFARRTHATQKNTFGWIRAEVMGALVNAIFLTGLCFAILLEAIERF
IEPHEMQQPLVVLGVGVAGLLVNVLGLCLFHHGHSHGGHGHGHDRAGQLN
MRGVFLHVLGDALGSVIVVVNALVFYFSWKGCSEGDFCVNPCFPDPCKAY
EAGPCWVLYLDPTLCVVMVCILLYTTYPLLKESALILLQTVPKQIDIRNL
IKELRNVEGVEEVHELHVWQLAGSRIIATAHIKCEDPTSYMEVAKTIKDV
FHNHGIHATTIQPEF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8zsz Chain B Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8zsz Zinc transporter 1 functions in copper uptake and cuproptosis.
Resolution3.59 Å
Binding residue
(original residue number in PDB)		H43 D47 H251 D255
Binding residue
(residue number reindexed from 1)		H39 D43 H157 D161
Annotation score5
External links
PDB RCSB:8zsz, PDBe:8zsz, PDBj:8zsz
PDBsum8zsz
PubMed39111308
UniProtQ9Y6M5|ZNT1_HUMAN Proton-coupled zinc antiporter SLC30A1 (Gene Name=SLC30A1)

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