Structure of PDB 8yrs Chain B Binding Site BS03

Receptor Information
>8yrs Chain B (length=530) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLV
MPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARR
FTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVL
TDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRY
KGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSA
NEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKA
DCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHF
DEVWNSEACNKMCDNCCKGSAFERKNITEYCRDLIKILKQAEELNEKLTP
LKLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFT
AYATISYLKIGPKANLLNNEAHAITMQVTK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8yrs Chain B Residue 900 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8yrs Crystal structure of human RECQ1 helicase containing a flexible linker in complex with tailed duplex DNA
Resolution2.43 Å
Binding residue
(original residue number in PDB)		C453 C471 C475 C478
Binding residue
(residue number reindexed from 1)		C391 C409 C413 C416
Annotation score1
External links
PDB RCSB:8yrs, PDBe:8yrs, PDBj:8yrs
PDBsum8yrs
PubMed
UniProtP46063|RECQ1_HUMAN ATP-dependent DNA helicase Q1 (Gene Name=RECQL)

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