Structure of PDB 8xrf Chain B Binding Site BS03

Receptor Information

>8xrf Chain B (length=774) Species: 10498 (African swine fever virus BA71V) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VDVDKYTRARNAGGKRAQDCMLLAAEGDSALSLLRTGLTLGKSNPSGPSF
DFCGMISLGGVIMNACKKVTNITIMVRNEQLTNNKVLQGIVQVLGLDFNC
HYKTQEERAKLRYGCIVACVDQDLDGCGKILGLLLAYFHLFWPQLIIHGF
VKRLLTPLIRVYEKGKTMPVEFYYEQEFDAWAKKQTSLVNHTVKYYKGLA
AHDTHEVKSMFKHFDNMVYTFTLDDSAKELFHIYFGGESELRKRELCTGV
VPLTETQTQSIHSVRRIPCSLHLQVDTKAYKLDAIERQIPNFLDGMTRAR
RKILAGGVKCFASNNRERKVFQFGGYVADHMFYHHGDMSLNTSIIKAAQY
YPGSSHLYPVFIGIGSFGSRHLGGKDAGSPRYISVQLASEFIKTMFPAED
SWLLPYVFEDGQRAEPEYYVPVLPLAIMEYGANPSEGWKYTTWARQLEDI
LALVRAYVDKDNPKHELLHYAIKHKITILPLRPSNYNFKGHLKRFGQYYY
SYGTYDISEQRNIITITELPLRVPTVAYIESIKKSSNRMTFIEEIIDYSS
SETIEILVKLKPNSLNRIVEEFKETEEQDSIENFLRLRNCLHSHLNFVKP
KGGIIEFNSYYEILYAWLPYRRELYQKRLMREHAVLKLRIIMETAIVRYI
NESAELNLSHYEDEKEASRILSEHGFPPLNHTLIISPEFASIEELNQKAL
QGCYTYILSLQARELLIAAKTRRVEKIKKMQARLDKVEQLLQESPFPGAS
VWLEEIDAVEKAIIKGRNTQWKFH

Ligand information

>8xrf Chain F (length=15) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cgcgaatcgtcatcc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8xrf The crystal structure of AsfvTopII in complex with G-DNA
Resolution	2.94 Å
Binding residue (original residue number in PDB)	K417 G439 D440 S441 G472 M756
Binding residue (residue number reindexed from 1)	K5 G27 D28 S29 G60 M338

External links

PDB	RCSB:8xrf, PDBe:8xrf, PDBj:8xrf
PDBsum	8xrf
PubMed
UniProt	Q00942\|TOP2_ASFB7 DNA topoisomerase 2 (Gene Name=TOP)

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