Structure of PDB 8slf Chain B Binding Site BS03

Receptor Information

>8slf Chain B (length=436) Species: 1078020 (Mycolicibacterium thermoresistibile ATCC 19527)

ASIIDTVANLAKRRGFVYQSGEIYGGTRSAWDYGPLGVELKENIKRQWWK
SMVTAREDVVGIDTSIILPREVWVASGHVDVFHDPLVECLNCHRRHRQDH
VVCPDCGTWTEPREFNMMLKTYLGPIESDEGLHYLRPETAQGIFTNFANV
VTTARKKPPFGIAQTGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAK
EWHQYWIDTRLQWYVDLGIDRDNLRLYEHPPEKLSHYAERTVDIEYKYGF
AGDPWGELEGIANRTDFDLSTHSKHSGVDLSYYDQATDTRYVPYVIEPAA
GLTRSLMAFLIDAYSEDEAPNAKGGVDKRTVLRFDPRLAPVKVAVLPLSR
HADLSPKARDLAAELRQHWNVEFDDAGAIGRRYRRQDEVGTPYCVTVDFD
SLEDNAVTVRERDSMAQERISIDQVTDYLAVRLKGC

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8slf Chain B Residue 503

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8slf Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (AMP bound)
• Resolution: 2.9 Å
• Binding residue (original residue number in PDB): V54 R57
• Binding residue (residue number reindexed from 1): V53 R56
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 6.1.1.14: glycine--tRNA ligase.

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0004812 aminoacyl-tRNA ligase activity
• GO:0004820 glycine-tRNA ligase activity
• GO:0005524 ATP binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation
• GO:0006418 tRNA aminoacylation for protein translation
• GO:0006426 glycyl-tRNA aminoacylation

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:8slf, PDBe:8slf, PDBj:8slf
• PDBsum: 8slf
• UniProt: G7CIG9