Structure of PDB 8rn4 Chain B Binding Site BS03

Receptor Information

>8rn4 Chain B (length=722) Species: 1601067 (Influenza B virus (B/Memphis/13/2003)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MNINPYFLFIDVPIQAAISTTFPYTGVPPYSHGTGTGYTIDTVIRTHEYS
NKGKQYISDVTGCTMVDPTNGPLPEDNEPSAYAQLDCVLEALDRMDEEHP
GLFQAASQNAMETLMVTTVDKLTQGRQTFDWTVCRNQPAATALNTTITSF
RLNDLNGADKGGLIPFCQDIIDSLDRPEMTFFSVKNIKKIKRIPMKVKDK
ITKVEYIKRALSLNTMTKDAERGKLKRRAIATAGIQIRGFVLVVENLAKN
ICENLEQSGLPVGGNEKKAKLSNAVAKMLSNCPPGGISMTVTGDNTKWNE
CLNPRIFLAMTERITRDSPIWFRDFCSIAPVLFSNKIARLGKGFMITSKT
KRLKAQIPCPDLFSIPLERYNEETRAKLKKLKPFFNEEGTASLSPGMMMG
MFNMLSTVLGVAALGIKNIGNKEYLWDGLQSSDDFALFVNAKDEETCMEG
INDFYRTCKLLGINMSKKKSYCNETGMFEFTSMFYRDGFVSNFAMELPSF
GVAGVNESADMAIGMTIIKNNMINNGMGPATAQTAIQLFIADYRYTYKCH
RGDSKVEGKRMKIIKELWENTKGRDGLLVADGGPNIYNLRNLHIPEIVLK
YNLMDPEYKGRLLHPQNPFVGIKEADKKMDYDAVSGTHSWRTKRNTDQRN
MILEEQCYAKCCNLFEACFNSASYRKPVGQHSMLEAMAHRLRMDARLDYE
SGRMSKDDFEKAMAHLGEIGYI

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8rn4 Chain B Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8rn4 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase.
Resolution	2.87 Å
Binding residue (original residue number in PDB)	G304 D445
Binding residue (residue number reindexed from 1)	G293 D434
Annotation score	1

External links

PDB	RCSB:8rn4, PDBe:8rn4, PDBj:8rn4
PDBsum	8rn4
PubMed	39160148
UniProt	Q5V8Y6

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