Structure of PDB 8qmf Chain B Binding Site BS03

Receptor Information
>8qmf Chain B (length=674) Species: 196600 (Vibrio vulnificus YJ016) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDRKHLANAIRALSMDGVQKANSGHPGAPMGMADIAEVLWRGHLNHNPSN
PEWADRDRFVLSNGHGSMLIYSLLHLSGYELSIDDLKNFRQLHSKTPGHP
EYGYAPGIETTTGPLGQGITNAVGMAMAEKALAAQFNKEGHDIVDHFTYV
FMGDGCLMEGISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFSDDT
PKRFEAYGWHVIPAVDGHNAEAINAAIEAAKADPRPTLICTKTIIGFGSP
NKSGSHDCHGAPLGAEEIAATRKELGWEHGPFEIPQEVYAEWSAKEAGAA
KEAAWNEKFAAYEAAYPELAAEFKRRVNGELPAQWEEKANQIIADLQANP
ANIASRKASQNALEAFGKMLPEFMGGSADLAPSNLTMWSGSKSLEASDFS
GNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALM
KVQNIQVYTHDSIGLGEDGPTHQPVEQIASLRLTPNMSTWRPCDQVESAV
AWKLAIERKDGPSALIFSRQNLAQQERTAEQVADIAKGGYILKDSDGKPE
LILIATGSEVELAVKAAEQLTAEGKKVRVVSMPATDAFDKQDAAYRESVL
PSDVTARIAIEAGITDFWYKYVGFDGRIIGMTTFGESAPADQLFEMFGFT
VENVVNTAKELLAENLYFQGLEHH
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8qmf Chain B Residue 708 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8qmf Structural determination and kinetic analysis of the Transketolase from Vibrio vulnificus reveal unexpected cooperative behavior.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D154 N184 I186
Binding residue
(residue number reindexed from 1)		D154 N184 I186
Annotation score1
Enzymatic activity
Enzyme Commision number 2.2.1.1: transketolase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004802 transketolase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006098 pentose-phosphate shunt
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qmf, PDBe:8qmf, PDBj:8qmf
PDBsum8qmf
PubMed38145310
UniProtQ7MDD4|TKT2_VIBVY Transketolase 2 (Gene Name=tkt2)

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