Structure of PDB 8p0u Chain B Binding Site BS03

Receptor Information
>8p0u Chain B (length=587) Species: 11569 (Thogotovirus thogotoense) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNLFTPRSEINPTTTQELLYAYTGPAPVAYGTRTRAVLENIIRPYQYFYK
EPNVQRALDIKTGCKEPEDINVEGPSSGFHTASVLKLADNFFRKYRPAME
KLKYWILVKLPKLKYAELSKGRQTYSFIHKRNLPAPIALEETVEFLEQNL
RRKIGPTLLSYCQAIADVMELDETTYEGATYTIKFSREELWDQMRTLNTM
WKHLERGRLNRRTIATPSMLIRGFVKIVEDAAKEILENVPTSGVPVGGEE
KLAKLASKQTFHTAVTGELSGDQEKFNECLDPDAMRLMWTVFLRKLGCPD
WIMELFNIPFMVFKSKLADMGEGLVYTKGKLTDRKPLGEMPSEFDDLVRN
VVGNSISCRLGMFMGMYNLTSTLLALISIEREELTGSHVESSDDFIHFFN
CKTHEEMFKQAETLRLTLKLVGINMSPSKCILISPAGIGEFNSKFHHRDF
VGNVATELPALVPNGTNPMTDLAMGLNVIKHSVNTGQMNLCTGALAMRIF
NHAYKYAYMALGVTRRTRFMEENAITPLLTNQGASPVHSFSTMHLDEVAL
RRHLGLLDEETLRRILNPNNPVTDYSVPSCFKYTLSR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8p0u Chain B Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8p0u Thogoto virus polymerase
Resolution2.92 Å
Binding residue
(original residue number in PDB)		G300 D301 D423 E469
Binding residue
(residue number reindexed from 1)		G271 D272 D394 E440
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003968 RNA-dependent RNA polymerase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8p0u, PDBe:8p0u, PDBj:8p0u
PDBsum8p0u
PubMed
UniProtO41353|RDRP_THOGV RNA-directed RNA polymerase catalytic subunit (Gene Name=Segment)

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