Structure of PDB 8ovj Chain B Binding Site BS03

Receptor Information
>8ovj Chain B (length=401) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHCKFEHPRHGHLGFLPRKRSRQIRGRARAFPKDDATQKPHLTSFMVFKA
GMTHIVRDVDRPGSKVNKKEVVEPVTILEAPPMVIVGIVGYRQTPVGLKT
IGTVWAHHTSVEFRRRYYKNWKQSAQLAFSRQKQFANTKEGKVAEARTLN
AFAKKASVIRVIAHTQLRKLRNHRVGVKKAHVQEIQVNGGSVAAKIALAK
SLLEKEVRVDSVFQQSEACDVCSVTKGHGTEGVVKRWGVACLPRKTHRGL
RKVACIGAWHPARVMYTVARAGQHGYHHRTQLNKKIYQIGRSVAVEPNQA
TTTYDLTAKTITPMGGFVGYGTVRNDYVMLKGSVSGPRRRVMTLRRPMAP
QTSRQLKEKIVLKFIDTSSKIGHGRFQTKKEKNQWFGPLKKDRIRREERL
R
Ligand information
>8ovj Chain 5 (length=115) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uacgucccucuccaaacgagagaacaugcaugggcuggcaugagcggcau
gcuucccgguggggcucgcgucccgaggcgcugaaccuugaggccugaaa
caugcucagggacac
...<<<<<<<<<.......>>>>....<<<<<<<<.<<.....<<<....
............<<..<..>..>>....>>>....>>.....>>>.....
>>>>>...>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ovj Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		R21 R117 K120 N121 K123 Q124 A126 R172 H174 R175 G177 V178 K179 K180 G228 G230 G316 G320 R340 R341 S370 K380 K383 F387 K391
Binding residue
(residue number reindexed from 1)		R20 R116 K119 N120 K122 Q123 A125 R171 H173 R174 G176 V177 K178 K179 G227 G229 G315 G319 R339 R340 S369 K379 K382 F386 K390
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ovj, PDBe:8ovj, PDBj:8ovj
PDBsum8ovj
PubMed38722744
UniProtQ4Q2Q6

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