Structure of PDB 8k7a Chain B Binding Site BS03

Receptor Information
>8k7a Chain B (length=563) Species: 171101 (Streptococcus pneumoniae R6) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSFIPILVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRST
LGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPM
SFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQN
TNLFFMTLLALPIYTVIIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGI
ETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHLLLNV
GILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVA
NNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDIN
LTVPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKK
ALRQYINYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDI
ERMPLNYQTELTSDGAGISGGQRQRIALARALLTDAPVIILDQATSSLDI
LTEKRIVDNLIALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGKHADL
LAQGGFYAHLVNS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8k7a Chain B Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8k7a Nucleotide-bound ComA E647Q with Mg2+
Resolution4.2 Å
Binding residue
(original residue number in PDB)		T524 Q565
Binding residue
(residue number reindexed from 1)		T370 Q411
Annotation score1
Enzymatic activity
Enzyme Commision number 3.4.22.-
7.4.2.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0016887 ATP hydrolysis activity
GO:0034040 ATPase-coupled lipid transmembrane transporter activity
GO:0043214 ABC-type bacteriocin transporter activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0006508 proteolysis
GO:0006869 lipid transport
GO:0030420 establishment of competence for transformation
GO:0043213 bacteriocin transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8k7a, PDBe:8k7a, PDBj:8k7a
PDBsum8k7a
PubMed37935699
UniProtP59653|COMA_STRR6 Transport/processing ATP-binding protein ComA (Gene Name=comA)

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