Structure of PDB 8jxi Chain B Binding Site BS03

Receptor Information
>8jxi Chain B (length=148) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DWKCDNDNDCGDGSDELPTVCAFHTCRSTAFTCGNGRCVPYHYRCDYYND
CGDNSDEAGCLFRNCNSTTEFTCSNGRCIPLSYVCNGINNCHDNDTSDEK
NCPPHTCPPDFTKCQTTNICVPRAFLCDGDNDCGDGSDENPIYCASHT
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8jxi Chain B Residue 4706 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8jxi Cryo-EM structures elucidate the multiligand receptor nature of megalin.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		Y2799 V2800 N2802 I2804 N2806 D2814 E2815
Binding residue
(residue number reindexed from 1)		Y83 V84 N86 I88 N90 D98 E99
Annotation score4
External links
PDB RCSB:8jxi, PDBe:8jxi, PDBj:8jxi
PDBsum8jxi
PubMed38771880
UniProtP98158|LRP2_RAT Low-density lipoprotein receptor-related protein 2 (Gene Name=Lrp2)

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