Structure of PDB 8jq5 Chain B Binding Site BS03

Receptor Information
>8jq5 Chain B (length=421) Species: 47715 (Lacticaseibacillus rhamnosus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVKPEEVDKAYEVAKQRYAEIGVDTDAAMKELEKVPLSVHCWQGDDIHGF
LFPNQELTGGIGVSGNYPGIARTPDELAGDMHEALSLIPGKHRVQLHAIY
AVTDKKRDLDTLEPEDFDYWIDWAKQEGVGLDFNGTFFSHPMVKDNMTVS
SPDPKVRDFWIRHGKISREISNYIGEKLGSQVVNNFWLPDGFKDNPIDKK
TPRLRLLKALDEIIKDPLPEKNTIESFEGKLFGTGIESYTTGSHEFYQNY
AISRNKLWTIDAGHFHPTEDVSDKFSAFFPFGKGLFMHVSRPVRWDSDHV
VIMDDALIRITRSLVRDGYLDRTHIGLDFFDATINRVAAWVVGARATQKS
LLQAMLAPIDQLKKDELNADFTTRLIETEELKSFPFGAVWDKFCQDHNTP
VGFDWMNNIHQYEKDVQFKRD
Ligand information
Ligand IDPSJ
InChIInChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5-,6+/m1/s1
InChIKeyBJHIKXHVCXFQLS-PUFIMZNGSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C([C@H]([C@H]([C@H](C(=O)CO)O)O)O)O
CACTVS 3.352OC[C@@H](O)[C@@H](O)[C@@H](O)C(=O)CO
ACDLabs 11.02O=C(C(O)C(O)C(O)CO)CO
OpenEye OEToolkits 1.7.0C(C(C(C(C(=O)CO)O)O)O)O
CACTVS 3.352OC[CH](O)[CH](O)[CH](O)C(=O)CO
FormulaC6 H12 O6
NameD-psicose
ChEMBLCHEMBL1235460
DrugBankDB15087
ZINCZINC000005132035
PDB chain8jq5 Chain B Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8jq5 X-ray structure and characterization of a probiotic Lactobacillus rhamnosus Probio-M9 L-rhamnose isomerase.
Resolution1.73 Å
Binding residue
(original residue number in PDB)		I61 H97 W187 E228 K230 H264 D328 F330
Binding residue
(residue number reindexed from 1)		I61 H97 W187 E228 K230 H264 D328 F330
Annotation score2
Enzymatic activity
Enzyme Commision number 5.3.1.14: L-rhamnose isomerase.
Gene Ontology
Molecular Function
GO:0008740 L-rhamnose isomerase activity
GO:0016853 isomerase activity
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
Biological Process
GO:0019299 rhamnose metabolic process
GO:0019301 rhamnose catabolic process
GO:0019324 L-lyxose metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jq5, PDBe:8jq5, PDBj:8jq5
PDBsum8jq5
PubMed38430263
UniProtA0A171J5T1

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