Structure of PDB 8d8n Chain B Binding Site BS03

Receptor Information
>8d8n Chain B (length=1256) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHKQEKNDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTY
TGRITLRNEHAKKLLLASLGFVDKLCGALCRIEVIKKEVLSEDHNDELRK
QAEVIVEAFKQNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDK
GHHLWDIKVQGTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETG
IETKEWIIVGRLKAATPFYFGVQQPSDSIPGVINEHTSFNILLDKENRYR
IPRSALRGALRRDLRTAFGSGCNVSLGGQILCNCKVCIEMRRITLKDSVS
DFSEPPEIRYRIAKNPGTATVEDGSLFDIEVGPEGLTFPFVLRYRGHKFP
EQLSSVIRYWEENDGKNGMAWLGGLDSTGKGRFALKDIKIFEWDLNQKIN
EYIKERGMRGKEKELLEMGESSLPDGLIPYKFFEERECLFPYKENLKPQW
SEVQYTIEVGSPLLTADTISALTEPGNRDAIAYKKRVYNDGNNAIEPEPR
FAVKSETHRGIFRTAVGRRTGDLGKEDHEDCTCDMCIIFGNEHESSKIRF
EDLELINGNEFEKLEKHIDHVAIDRFTGGALDKAKFDTYPLAGSPKKPLK
LKGRFWIKKGFSGDHKLLITTALSDIRDGLYPLGSKGGVGYGWVAGISID
DNVPDDFKEMINKTEGPINNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGS
KVYREKDIITHEEFTEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNK
PGHKNYKFFNINGELMIPGSELRGMLRTHFEALTKSCFAIFGEDSTLSWR
RKCASKTLGGKLDKALHPCTGLSDGLCPGCHLFGTTDYKGRVKFGFAKYE
NGPEWLITRGNNPERSLTLGVLESPRPAFSIPDDESEIPGRKFYLHHNGW
RIIRQKQLEIRETVQPERNVTTEVMDKGNVFSFDVKFENLREWELGLLLQ
SLDPGKNIAHKLGKGKPYGFGSVKIKIDSLHTFKINSNNDKIKRVPQSDI
REYINKGYQKLIEWSGNNSIQKGNVLPQWHVIPHIDKLYKLLWVPFLNDS
KLEPDVRYPVLNEESKGYIEGSDYTYKKLGDKDNLPYKTRVKGLTTPWSP
WNPFQV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8d8n Chain B Residue 1801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8d8n Craspase is a CRISPR RNA-guided, RNA-activated protease.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		C83 I115 C116
Binding residue
(residue number reindexed from 1)		C83 I115 C116
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:8d8n, PDBe:8d8n, PDBj:8d8n
PDBsum8d8n
PubMed36007061
UniProtA0A0B0EGF3

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