Structure of PDB 8csp Chain B Binding Site BS03

Receptor Information

>8csp Chain B (length=220) Species: 9606 (Homo sapiens)

STDFNDKILNEPLKHSDFFNVKELFSVRSLFDARVHLGHKAGCRHRFMEP
YIFGSRLDHDIIDLEQTATHLQLALNFTAHMAYRKGIILFISRNRQFSYL
IENMARDCGEYAHTRYFRGGMLTNARLLFGPTVRLPDLIIFLHTLNNIFE
PHVAVRDAAKMNIPTVGIVDTNCNPCLITYPVPGNDDSPLAVHLYCRLFQ
TAITRAKEKRQQVEALYRLQ

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8csp Chain B Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8csp Principles of mitoribosomal small subunit assembly in eukaryotes.
• Resolution: 2.66 Å
• Binding residue (original residue number in PDB): H93 D240 D241
• Binding residue (residue number reindexed from 1): H39 D186 D187
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation
• GO:0032543 mitochondrial translation
• GO:0061668 mitochondrial ribosome assembly

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0005759 mitochondrial matrix
• GO:0005763 mitochondrial small ribosomal subunit
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8csp, PDBe:8csp, PDBj:8csp
• PDBsum: 8csp
• PubMed: 36482135
• UniProt: Q9Y399|RT02_HUMAN Small ribosomal subunit protein uS2m (Gene Name=MRPS2)