Structure of PDB 8bws Chain B Binding Site BS03

Receptor Information
>8bws Chain B (length=1104) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DEINTAQDKWHLLPAFLKVKGLVKQHLDSFNYFVDTDLKKIIKANQLILS
DVDPEFYLKYVDIRVGKKSSSSTKDYLTPPHECRLRDMTYSAPIYVDIEY
TRGRNIIMHKDVEIGRMPIMLRSNKCILYDADESKMAKLNECPLDPGGYF
IVNGTEKVILVQEQLSKNRIIVEADEKKGIVQASVTSSTHERKSKTYVIT
KNGKIYLKHNSIAEEIPIAIVLKACGILSDLEIMQLVCGNDSSYQDIFAV
NLEESSKLDIYTQQQALEYIGAKVKTMRRQKLTILQEGIEAIATTVIAHL
TVEALDFREKALYIAMMTRRVVMAMYNPKMIDDRDYVGNKRLELAGQLIS
LLFEDLFKKFNNDFKLSIDKVLKKPNRAMEYDALLSINVHSNNITSGLNR
AISTGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKSRKVSG
PRALQPSQFGMLCTADTPEGEACGLVKNLALMTHITTDDEEEPIKKLCYV
LGVEDITLIDSASLHLNYGVYLNGTLIGSIRFPTKFVTQFRHLRRTGKVS
EFISIYSNSHQMAVHIATDGGRICRPLIIVSDGQSRVKDIHLRKLLDGEL
DFDDFLKLGLVEYLDVNEENDSYIALYEKDIVPSMTHLEIEPFTILGAVA
GLIPYPHHNQSPRNTYQCAMGKQAIGAIAYNQFKRIDTLLYLMTYPQQPM
VKTKTIELIDYDKLPAGQNATVAVMSYSGYDIEDALVLNKSSIDRGFGRC
ETRRKTTTVLKRYANHTQDIIGGMRVDENGDPIWQHQSLGPDGLGEVGMK
VQSGQIYINKSVPTNSAQTQYREAPVIYRGPEPSHIDQVMMSVSDNDQAL
IKVLLRQNRRPELGDKFSSRHGQKGVCGIIVKQEDMPFNDQGIVPDIIMN
PHGFPSRMTVGKMIELISGKAGVLNGTLEYGTCFGGSKLEDMSKILVDQG
FNYSGKDMLYSGITGECLQAYIFFGPIYYQKLKHMVLDKMHARARGPRAV
LTRQPTEGRSRDGGLRLGEMERDCVIAYGASQLLLERLMISSDAFEVDVC
DKCGLMGYSGWCTTCKSAENIIKMTIPYAAKLLFQELLSMNIAPRLRLED
IFQQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8bws Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		G453 H456 E504 Q708 K919 H1029
Binding residue
(residue number reindexed from 1)		G418 H421 E469 Q673 K874 H984
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006383 transcription by RNA polymerase III
GO:0006384 transcription initiation at RNA polymerase III promoter
GO:0006386 termination of RNA polymerase III transcription
GO:0042797 tRNA transcription by RNA polymerase III
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005666 RNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bws, PDBe:8bws, PDBj:8bws
PDBsum8bws
PubMed36977686
UniProtP22276|RPC2_YEAST DNA-directed RNA polymerase III subunit RPC2 (Gene Name=RET1)

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