Structure of PDB 8btg Chain B Binding Site BS03

Receptor Information

>8btg Chain B (length=335) Species: 1423 (Bacillus subtilis)

NMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKT
HLMHAIGHYVIDHNPSAKVVYLSSEKFTNEFINSIRDNKAVDFRNRYRNV
DVLLIDDIQFLAGKEQTQEEFFHTFNTLHEESKQIVISSDRPPKEIPTLE
DRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMLYIANQI
DSNIRELEGALIRVVAYSSLINKDINADLAAEALKDISKPKVITIKEIQR
VVGQQFNIKLEDFKAKKRTKSVAFPRQIAMYLSREMTDSSLPKIGEEFGG
RDHTTVIHAHEKISKLLADDEQLQQHVKEIKEQLK

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8btg Chain B Residue 500

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8btg The bacterial replication origin BUS promotes nucleobase capture.
• Resolution: 3.2 Å
• Binding residue (original residue number in PDB): K157 D214 S246
• Binding residue (residue number reindexed from 1): K49 D106 S138
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0003688 DNA replication origin binding
• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity
• GO:0042802 identical protein binding
• GO:0043565 sequence-specific DNA binding

Biological Process

• GO:0006260 DNA replication
• GO:0006270 DNA replication initiation
• GO:0006275 regulation of DNA replication

Cellular Component

• GO:0005737 cytoplasm
• GO:0005886 plasma membrane
• GO:1990101 DnaA-oriC complex

External links

• PDB: RCSB:8btg, PDBe:8btg, PDBj:8btg
• PDBsum: 8btg
• PubMed: 38097584
• UniProt: P05648|DNAA_BACSU Chromosomal replication initiator protein DnaA (Gene Name=dnaA)