Structure of PDB 8b70 Chain B Binding Site BS03

Receptor Information
>8b70 Chain B (length=572) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QKLTKLKALAMLSSDALSSVAYGTEQILIILATISAAAFWYSIPIAVGVL
ILLLALILSYRQIIYAYPQGGGAYIVSKENLGEKPGLIAGGSLLVDYILT
VAVSISAGTDAITSAFPALHDYHVPIAIFLVLVIMILNLRGLASILAYPV
YLFVVALLVLIAVGLFKLMTGQGTPVAGITLFLLLKAFSSGCSALTGVEA
ISNAIPAFKNPPARNAARTLAMMGILLAILFSGITVLAYGYGTAPKPDET
VVSQIASETFGRNVFYYVIQGVTSLILVLAANTGFSAFPQLAFNLARDQY
MPRMFTVRGDRLGFSNGIIFLGFASIVLIILFGGQTEHLIPLYAVGVFIP
FTLSQTGMCMKWIKQKPKGWIGKMLINSCGALISFMVLSILFVTKFNVVW
PVLIFMPIVVLLFFAIKNHYTAVGEQLRIVDKEPEEIKGTVVIVPVAGVT
TVVQKSIHYAKSLSDQVIAVHVSFDREQEKKFEKRWEELNNGVRLVTLHS
SYRSLVHPFDKFLETVEAKAKKEQFSVMVLFPQFITKKRWHTILHNQSAF
LLRVRLFWKKDIMVATLPYHFK
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain8b70 Chain B Residue 903 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8b70 Cyclic di-AMP traps proton-coupled K + transporters of the KUP family in an inward-occluded conformation.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		D36 S40 Y43 T230 Y377
Binding residue
(residue number reindexed from 1)		D15 S19 Y22 T196 Y343
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015293 symporter activity
GO:0022857 transmembrane transporter activity
GO:0046872 metal ion binding
Biological Process
GO:0006813 potassium ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8b70, PDBe:8b70, PDBj:8b70
PDBsum8b70
PubMed37344476
UniProtP96589|KIMA_BACSU Potassium transporter KimA (Gene Name=kimA)

[Back to BioLiP]