Structure of PDB 8b4h Chain B Binding Site BS03

Receptor Information
>8b4h Chain B (length=358) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MITRGEFFMIKEMYERGMSISDIARELGIDRKTVRKYIHSPNPPSKSKRK
QRKSKLDPFKPYLQKRMLEDGVFNSEKLFFEIRQQGYTGGKTILKDYMKP
FRETAKKKYTVRYETLPGEQMQVDWKEVGEVVIEGKKVKLSLFVATLGYS
RMKYAVFTTSQDQEHLMECLIQSFKYFGGVPKKVLFDNMKTVTDGREQGV
VKWNQRFSEFASYYGFIPKVCRPYRAQTKGKVERAIQYIMDHFYVGTAFE
SIEELNFLLHRWLDQVANRKPNATTGISPQERWAEESLKPLPLKDYDTSY
LSYRKVHWDGSFSYKGEQWLLSAEYAGKEILVKERLNGDIRLYFRGEEIS
HVDQQKKV
Ligand information
>8b4h Chain G (length=57) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
catgtcaaggccgattattttttccccaaaatcgccggtttaaaattccc
cagaagg
Receptor-Ligand Complex Structure
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PDB8b4h IS21 family transposase cleaved donor complex traps two right-handed superhelical crossings.
Resolution3.35 Å
Binding residue
(original residue number in PDB)		T110 V111 R112 Y113 R151 R222 R225 Q227 G230 K231 R234 Y238 D241 K270 T274
Binding residue
(residue number reindexed from 1)		T110 V111 R112 Y113 R151 R222 R225 Q227 G230 K231 R234 Y238 D241 K270 T274
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000150 DNA strand exchange activity
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration
GO:0032196 transposition

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Molecular Function
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Biological Process
External links
PDB RCSB:8b4h, PDBe:8b4h, PDBj:8b4h
PDBsum8b4h
PubMed37087515
UniProtQ45618|TRA6_GEOSE Putative transposase for insertion sequence element IS5376

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