Structure of PDB 8ay6 Chain B Binding Site BS03

Receptor Information
>8ay6 Chain B (length=314) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CIPLWGTVSIQGNRSEMEDAFAVSPHFLKLPIKMLMGDHEESPSLTHLTG
HFFGVYDGHGGHKVADYCRDRLHFALAEEIERIKDELTGEGRQVQWDKVF
TSCFLTVDGEIEGKIGRAVVDKVLEAVASETVGSTAVVALVCSSHIVVSN
CGDSRAVLFRGKEAMPLSVDHKPDREDEYARIENAGGKVIQWQGARVFGV
LAMSRSIGDRYLKPYVIPEPEVTFMPRSREDECLILASDGLWDVMNNQEV
CEIARRRILMWHKKNGAPPLAERGKGIDPACQAAADYLSMLALQKGSKDN
ISIIVIDLKAQRKF
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain8ay6 Chain B Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8ay6 Structure-guided engineering of a receptor-agonist pair for inducible activation of the ABA adaptive response to drought.
Resolution1.84 Å
Binding residue
(original residue number in PDB)		D432 D436
Binding residue
(residue number reindexed from 1)		D239 D243
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
GO:0043169 cation binding
Biological Process
GO:0006470 protein dephosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8ay6, PDBe:8ay6, PDBj:8ay6
PDBsum8ay6
PubMed36897942
UniProtQ9CAJ0|P2C16_ARATH Protein phosphatase 2C 16 (Gene Name=HAB1)

[Back to BioLiP]