Structure of PDB 8a3w Chain B Binding Site BS03

Receptor Information
>8a3w Chain B (length=395) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HPRHGHLGFLPRKRSRQIRGRARAFPKDDATQKPHLTSFMVFKAGMTHIV
RDVDRPGSKVNKKEVVEPVTILEAPPMVIVGIVGYRQTPVGLKTIGTVWA
HHTSVEFRRRYYKNWKQSAQLAFSRQKQFANTKEGKVAEARTLNAFAKKA
SVIRVIAHTQLRKLRNHRVGVKKAHVQEIQVNGGSVAAKIALAKSLLEKE
VRVDSVFQQSEACDVCSVTKGHGTEGVVKRWGVACLPRKTHRGLRKVACI
GAWHPARVMYTVARAGQHGYHHRTQLNKKIYQIGRSVAVEPNQATTTYDL
TAKTITPMGGFVGYGTVRNDYVMLKGSVSGPRRRVMTLRRPMAPQTSRQL
KEKIVLKFIDTSSKIGHGRFQTKKEKNQWFGPLKKDRIRREERLR
Ligand information
>8a3w Chain 4 (length=158) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggaucucgcagguaucgugagggaaguaugggguauacgggaacuccca
ugccgugccucuaguuucugggguuugucgaacggcaagugccccgaagc
caucgcacggugguucucggcugaaagccagaagccaaucccaagaccag
augcccac
<<<..>>>...<<<<<<....<<<<.<<<<<<<<...........>>>>>
>>><<<<<...<.<<....<<<<<<<<<......>>>>..>>>>>...>>
.>..>>>>>.<<<<....<<<<...>>>>....>>>>.>>>>.......>
>>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a3w CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE
Resolution2.89 Å
Binding residue
(original residue number in PDB)		G12 H13 L14 G15 R26 R30 K50 M53 H55 R62 P75 Y92 L99 T101 I102 G103 T104 W106 L128 A129 F130 R132 R161 E185 T226 K227 H279 R280 T281 L283 V335 S336 G373
Binding residue
(residue number reindexed from 1)		G5 H6 L7 G8 R19 R23 K43 M46 H48 R55 P68 Y85 L92 T94 I95 G96 T97 W99 L121 A122 F123 R125 R154 E178 T219 K220 H272 R273 T274 L276 V328 S329 G366
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8a3w, PDBe:8a3w, PDBj:8a3w
PDBsum8a3w
PubMed
UniProtQ4Q2Q6

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